Premature Centromeric Division and Abortions
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چکیده
منابع مشابه
Premature Centromeric Division and Abortions
An increased frequency of mitoses with centromere separation affecting all chromosomes was found in lymphocyte cultures of couples with recurrent spontaneous abortions. This anomaly was recorded in six individuals out of seventy couples (one hundred and forty individuals) with recurrent miscarriages. The abnormal behaviour of centromeres may predispose the individual to cell division errors, th...
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Chromosome segregation requires centromeres on every sister chromatid to correctly form and attach the microtubule spindle during cell division. Even though centromeres are essential for genome stability, the underlying centromeric DNA is highly variable in sequence and evolves quickly. Epigenetic mechanisms are therefore thought to regulate centromeres. Here, we show that the 359-bp repeat sat...
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ژورنال
عنوان ژورنال: INTERNATIONAL JOURNAL OF HUMAN GENETICS
سال: 2001
ISSN: 0972-3757,2456-6330
DOI: 10.31901/24566330.2001/01.03.06